Mary Beth Barone is a comedian, writer and actress from New York. In March 2021 she made her late-night television debut on The Tonight Show Starring Jimmy Fallon and toured with Chelsea Handler and Jenny Slate. Mary Beth has sold out shows at the New York Comedy Festival, the Netflix Is a Joke Festival and the Edinburgh Fringe. Most recently her feature screenplay You're My Best Friend was named to the 2022 Black List. Mary Beth has appeared on HBO Max's That Damn Michael Che, MTV's Catfish and various Comedy Central comedy specials. She co-hosted the popular Spotify podcast Obsessed with Benito Skinner. In 2023 the pair will launch their new podcast. She is also the creator and host of Drag His Ass: A F*ckboy Treatment Program, which runs regularly live in New York, Los Angeles and at London's Soho Theatre.

Before coming to comedy, Mary Beth worked in venture capital.