Natalya Yevgenyevna Guseva is a young film actress of Soviet cinema of the 1980s, who gained wide fame after playing the role of Alisa Seleznyova in the cult children's five-part television film "Guest from the Future" directed by Pavel Arsenov. In 1983, a director came to the class where Natasha studied and asked the teacher to let the girls who read poetry well go to the studio. That is how Natasha ended up in the short film "Dangerous Trifles", commissioned by the traffic police. While the film was being dubbed, she was noticed by director Pavel Arsenov, who was looking for an actress for the main role of Alisa Seleznyova in the children's science fiction film "Guest from the Future".

The film became very popular, and the role of Alisa seemed to have been created for her, making her famous overnight. In 1983-1988 she appeared in five feature films. After school, Natasha, following her long-standing dream of becoming a biologist, entered the Institute of Fine Chemical Technology in the "biotechnology" department. She then began working at the Gamaleya Institute of Epidemiology and Microbiology. Currently she is a professional biochemist and head of production of immunobiological preparations. In 2008, after a twenty-year break, she took part in several film and television projects.