Until the age of 12, her family lived in Kazakhstan in the city of Shevchenko (since 1991 Aktau). After her parents' divorce, she moved to Ivanovo with her mother Valentina Pavlovna in 1995. In 1999, after graduating from school, she enrolled at the Ivanovo Regional College of Culture in the course of Tanzilya Rakhimzyanovna Shchekina, from which she graduated in 2003. Then Natalya moved to Moscow and got a job as a manager in a sporting goods store on Kutuzovsky Prospekt.

In 2007, she participated in the program "Two Stars" with Dmitry Koldun. In 2011, she began playing the role of the head of the department in the series "Univer. New Dorm" on the TNT television channel. In 2012, she received the "TopBeauty Cinema Awards" in the "Temptation" category. In 2018, she received the "Fashion People Awards" in the "Actress of the Year" category.