Ofelia Medina (born April 4, 1950) is a Mexican actress, singer, and screenwriter of Mexican films. She made her film debut in Mexico in 1968 with the film "La paz," and in Hollywood with "The Big Fix" ten years later. In 1977 she played a hunchback in the telenovela "Rina." In 1984 she portrayed Frida Kahlo in Paul Leduc's film about the artist. In Canada, Medina was nominated for a Genie Award for her work in the film "Diplomatic Immunity" in 1991.

Ofelia Medina has also performed in various theaters around the world. Since 2000, Ofelia has played Frida Kahlo in the play "Cada quien su Frida." In 2007 she came to Denmark, performing in Aarhus, Copenhagen, and Odense at the Jens Galschiøt gallery.