Andrea Di Stefano (born December 15, 1972) is an Italian actor.

Born in Rome, he moved to New York to study acting at the Actors Studio. In the United States he appeared in "The Smile," an independent film directed by Andrew Hunt.

He played the lead role in the 1997 film "The Prince of Homburg," directed by Marco Bellocchio, and was selected for the 1997 Cannes Film Festival program. He has appeared in such films as Dario Argento's "The Phantom of the Opera," Alex Infascelli's "Almost Blue," and Roberta Torre's "Angela."

He recently played the role of Giancarlo in Ferzan Ozpetek's film "Sacred Heart."