Catalina Sandino Moreno (born April 19, 1981) is a Colombian actress. She is best known for her Academy Award nomination for Best Actress and for winning the Silver Bear alongside Charlize Theron for her leading role in the film Maria Full of Grace (2004).

Other credits include Fast Food Nation (2006), Love in the Time of Cholera (2007), Che (2008), The Twilight Saga: Eclipse (2010), Roa (2013), A Most Violent Year (2014), Falling Skies (2014), American Gothic (2016), Custody (2016), Jane the Virgin (2015–2019), The Catch (2020), Barbarians (2021), From (2022), Silent Night (2023), and Ballerina (2024).