Eugene Domingo (born Eugene Roxas Domingo, July 23, 1971) is a Filipino actress and television host. She is best known for her roles in the film franchises Ang Tanging Ina (2003-2011), Kimmy Dora (2009-2012), and Ang Babae sa Septic Tank (2011-2019), as well as in the films Here Comes the Bride (2010), Barber's Tales (2014), Ten Little Mistresses (2023), And the Breadwinner Is...

(2024), and Kontrabida Academy (2025). Domingo has been nominated for the Gawad Urian Award six times and has won the FAMAS Award twice.