Ntare Guma Mbaho Mwine will soon appear in two eagerly anticipated new series. First, he stars alongside Taron Egerton in the new AppleTV series "Smoke" from acclaimed writer Dennis Lehane, premiering June 27. Mwine also stars alongside Michael C. Hall in the Paramount+/Showtime series "Dexter: Resurrection" from acclaimed writers Clyde Phillips and Scott Reynolds, which also arrives in summer 2025. Previously, Mwine appeared alongside Rachel Weisz in Alice Birch's 2024 Peabody Award-winning series "Dead Ringers" on Amazon, based on David Cronenberg's 1988 thriller. Mwine also played Detective Raymond Griggs in the hit Netflix series "The Lincoln Lawyer" from David E. Kelley and Ted Humphrey, based on Michael Connelly's bestsellers. Mwine's extensive television credits include his critically acclaimed portrayal of Ronnie, a complex antihero, in Lena Waithe's Showtime series "The Chi." Variety, The Boston Globe, Roger Ebert and The New York Times have all singled out Mwine in their reviews, with the NY Times stating that "Mr. Mwine is especially notable as the precariously balanced Ronnie." Mwine starred in the finale of HBO's "Room 104" and previously had recurring roles on Steven Soderbergh's "The Knick" on Cinemax, David Simon and Eric Overmyer's "Treme" on HBO, Eric Overmyer's "Bosch" on Amazon, and Tim Kring's "Heroes" on NBC.

The Los Angeles Times named Mwine one of the breakout stars of Sundance 2020, and he received the (coveted) Best Actor award at the 2020 Durban International Film Festival for his leading role in Ekwa Msangi's award-winning film "Farewell Amor." Mwine was also singled out in Variety and The Hollywood Reporter reviews of the film, with the latter stating that "Mwine astonishes with his graceful pauses and piercing glances that seem to reach through the screen." In addition, the film was named one of the National Board of Review's top ten independent films.

Previous screen acting credits include Mira Nair's "Queen of Katwe" with Lupita Nyong'o and Ed Zwick's "Blood Diamond" with Leonardo DiCaprio. Mwine's work as a director of feature and short films has earned him numerous awards. His short film "Kuhani" won the top directing prize at the Oscar-qualifying International Short Film Festival Winterthur in Switzerland and was nominated for the Grand Prix for Best Short Film at Slamdance. Mwine's documentary feature "Memories of Love Returned" was named one of OkayAfrica's "top ten African documentaries of 2024." It has also won numerous awards, including the Audience Award for Best Documentary Feature at the Pan African Film Festival, Best Documentary at the Silicon Valley African Film Festival, and Best International Documentary and a Special Jury Mention at the International African Film Festival. The film chronicles the life and work of the late great Ugandan photographer Kibaate Aloysius Ssalongo, with Steven Soderbergh serving as executive producer.