Mary-Louise Parker (née le 2 août 1964) est une actrice et écrivaine américaine. Elle a reçu deux Tony Awards, deux Golden Globe Awards et un Primetime Emmy Award.

THÉÂTRE : The Sound Inside au Studio 54 (Tony Award) ; How I Learned to Drive (Obie et Lucille Lortel Awards et une nomination aux Outer Critics Circle), Heisenberg et The Snow Geese au Samuel J. Friedman Theatre ; Proof au Booth Theatre (Tony, Drama Desk, Outer Critics Circle, Drama League, Lucille Lortel, Obie et New York Magazine Awards), Prelude to a Kiss au Helen Hayes Theatre (nominations aux Tony et Drama Desk, Theatre World et The Clarence Derwent Award) ; Four Dogs and a Bone au New York City Centre ; Babylon Gardens au Circle Repertory Theatre ; The Art of Success au Manhattan Theatre Club ; Communicating Doors au Variety Arts Theatre, Reckless au Biltmore Theatre (nomination aux Tony) ; Hedda Gabler à l'American Airlines Theatre ; Bus Stop au Circle in the Square Theatre ; The Importance of Being Earnest au Hartford Stage ; Up in Saratoga à l'Old Globe Theatre ; et Hay Fever au Studio Arena Theatre.

TÉLÉVISION : The Institute, Weeds (Golden Globe Award, quatre nominations supplémentaires, trois nominations aux Emmy, six nominations aux SAG), Angels in America (Emmy, Golden Globe et Satellite Awards), The West Wing (nomination aux Emmy), The Robber Bride (nomination aux Emmy), Mr. Mercedes, When We Rise, Billions, Sugar Time, Saint Maybe et A Place for Annie.

CINÉMA : Omni Loop, Red Sparrow, Golden Exits, R.I.P.D, Red et Red 2, Behaving Badly, Pipe Dream, Chronically Metropolitan, Longtime Companion, Grand Canyon, Fried Green Tomatoes at the Whistle Stop Café, Naked in New York, The Client, Bullets over Broadway, Boys on the Side, Reckless, The Five Senses, Saved!, Romance & Cigarettes, Red Dragon, Solitary Man et Howl.