True O'Brien was born on February 28, 1994 in California. Her mother brought her into commercials at a very young age, when she was only 5 years old. At 13, she began modeling. She also participated in a perfume advertising campaign with Justin Bieber and even appeared as an extra in one of his music videos. In 2012, she had a bit part in one episode of the series Jessie (2011).

From March 3, 2014 to September 9, 2015, she played Paige Larson on the soap opera Days of Our Lives (1965).