Guido Quaroni began his career at Pixar Animation Studios in January 1997. For two years he worked on modeling, rigging, and shading for "Toy Story 2," and then moved on to work on effects for the film. Quaroni later became a sequence supervisor in the layout department for "Monsters, Inc.," where he worked on hair and effects technology. From there he went on to work with the Software Research and Development team, which he led for the asset/shading pipeline, and later as head of the Production Engineering team.

In January 2007, Quaroni became the technical director supervisor for the Academy Award-winning feature film "Toy Story 3." Quaroni was responsible for defining the various technologies used in the film, creating the production pipeline, and managing the various technical teams. He was also the technical director supervisor on "Monsters University."

In May 2011, Quaroni was promoted to vice president of Software R&D. In this role, he oversees the studio's graphics and animation software, including the Academy Award-winning animation software "Presto."

Quaroni also contributed voice work to the Golden Globe-winning film "Cars" as Guido, the Italian forklift. Quaroni returned to voice Guido in "Cars 2" in 2011 and "Cars 3" in 2017.